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ABOUT ME

I am a biomedical scientist in the US biopharma industry working in Alzheimer's Disease and Intestinal Bowel Disease. Before transitioning to my current position, I was a post-doctoral fellow with Dr. George Q. Daley, Dean of Harvard Medical School and Professor in the Stem Cell Program at Boston Children's Hospital. I was a graduate student, from 2009-2014, with Dr. Brian D. Strahl in the Department of Biochemistry and Biophysics at the University of North Carolina at Chapel Hill. I received my undergraduate degree in B.Sc Human Biology (Major: Biochemistry) from the All India Institute of Medical Sciences, New Delhi, India, and my  Masters in Life Sciences from the Jawaharlal Nehru University, New Delhi, India. 

My scientific interests broadly encompass how cells receive, process, and respond to both extrinsic and intrinsic signals. I am particularly interested in the fine-tuning of temporal and spatial control over gene expression and genome function through the regulation of chromatin structure and function. Specifically, I focus on how chromatin structure is regulated by functional and molecular interactions between DNA and histone modifications, transcription factors, and signaling molecules that collectively control cell fates and states. This field of study is commonly defined as 'epigenetics' (see relevant commentaries here and here). Over the years, I have become interested in human genetics, human "knock-outs", genome-wide association studies and applications of machine-learning in target discovery & validation. 

I have extensive expertise in studying fundamental molecular and cellular mechanisms, their dysfunction in diseases (e.g. cancer, cancer predisposition, autoimmunity, and neuro-inflammation), and novel strategies to target these mechanisms in disease conditions. In service of these goals, I use various model systems: human cell lines, induced pluripotent stem cells (iPS cells), mice, primary patient-derived cells, and microphysiological systems aka "organs-on-chips". Please see the publications section to get a flavor of my science. In addition to scientific R&D, I am interested in the business side of biopharma, especially venture-backed company creation, venture capital, and business development. 

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